What is the role of Intrauterine Insemination (IUI) in Infertility Treatment?

Around 1:7 couples experience difficulties in conceiving. This may be for many reasons, but intrauterine insemination (IUI) is an option for infertility treatment except when caused by tubal obstruction and severe male infertility.


In this procedure, prepared sperm is injected directly into the uterus via a fine catheter. The goal of IUI is to increase the number of sperm that reach the fallopian tubes and subsequently increase the chances of fertilization.


The overall success rate of IUI remains variable and depends on many factors. In some countries, IUI is being used increasingly less because of this but success rates up to 20% are reported by leading clinics, though 10-20% is considered an acceptable range.


The percentages in the upper part of this range (15-20%) are generally attained with the use of injectable fertility drugs, whereas IUI with low-cost clomiphene citrate is associated with lower success rates.


IUI can be classified as a “Low Tech” treatment option, which may suit some couples who either cannot or do not wish to commit to the physical and emotional stress of more “High Tech” artificial reproductive therapies (ARTs). IUI also comes at a relatively low cost and is convenient and simple.


IUI has been available as a treatment for many years and has changed relatively little. EVIE offers a step-change in IUI treatment, as it has been shown to improve pregnancy success rates compared with standard IUI treatment.